TEL: +86 571 56623320 EMAIL: [email protected]
Product Name PSG2 Chinese Name 妊娠特异性glycoprotein2抗体 Alias Pregnancy-specific beta-1 glycoprotein E; Pregnancy-specific beta-1-glycoprotein 2; Pregnancy-specific glycoprotein 2; PS-beta-E; PS-beta-G-2; PSBG-2; PSG2; PSG2_HUMAN. Research Area Cell biology Developmental biology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 37kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PSG2: 201-300/335 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]
Subcellular Location:
Secreted.
Similarity:
Belongs to the immunoglobulin superfamily. CEA family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
SWISS:
P11465
Gene ID:
5670
Database links:Entrez Gene: 5670 Human
Omim: 176391 Human
SwissProt: P11465 Human
Unigene: 709200 Human
Scan Wechat Qrcode