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Rabbit Anti-PSG2 antibody
Rabbit Anti-PSG2 antibody
Pregnancy-specific beta-1 glycoprotein E; Pregnancy-specific beta-1-glycoprotein 2; Pregnancy-specific glycoprotein 2; PS-beta-E; PS-beta-G-2; PSBG-2; PSG2; PSG2_HUMAN.
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  • NO.:SL19453R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,)
    Applications:IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name PSG2
Chinese Name 妊娠特异性glycoprotein2抗体
Alias Pregnancy-specific beta-1 glycoprotein E; Pregnancy-specific beta-1-glycoprotein 2; Pregnancy-specific glycoprotein 2; PS-beta-E; PS-beta-G-2; PSBG-2; PSG2; PSG2_HUMAN.  
Research Area Cell biology  Developmental biology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, )
Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 37kDa
Cellular localization Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human PSG2: 201-300/335 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]

Subcellular Location:
Secreted.

Similarity:
Belongs to the immunoglobulin superfamily. CEA family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:
P11465

Gene ID:
5670

Database links:

Entrez Gene: 5670 Human

Omim: 176391 Human

SwissProt: P11465 Human

Unigene: 709200 Human



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