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Rabbit Anti-PRSS56 antibody
Rabbit Anti-PRSS56 antibody
MCOP6; Protease serine 56; PRS56_HUMAN;Putative serine protease 56; Serine protease 56.
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  • NO.:SL19444R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Product Name PRSS56
Chinese Name 丝氨酸蛋白酶56抗体
Alias MCOP6; Protease serine 56; PRS56_HUMAN; Putative serine protease 56; Serine protease 56.  
Research Area Cell biology  Developmental biology  Neurobiology  Stem cells  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 63kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human PRSS56: 401-500/603 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a protein that contains a peptidase S1 domain and possesses trypsin-like serine protease activity. The encoded protein may play a role in eye development, and mutations in this gene are a cause of autosomal recessive posterior microphthalmos. [provided by RefSeq, Dec 2011]

Subcellular Location:
endoplasmic reticulum

Tissue Specificity:
Expressed neural retina, cornea, sclera and optic nerve.

DISEASE:
A developmental ocular disorder characterized by small malformed eyes. Clinical features are extreme hyperopia due to short axial length with essentially normal anterior segment, steep corneal curvatures, shallow anterior chamber, thick lenses, and thickened scleral wall. Palpebral fissures appear narrow because of relatively deep-set eyes, visual acuity is mildly to moderately reduced, and anisometropic or strabismic amblyopia is common. The fundus of the eye shows crowded optical disks, tortuous vessels, and an abnormal foveal avascular zone.

SWISS:
P0CW18

Gene ID:
646960

Database links:

Entrez Gene: 646960 Human

Entrez Gene: 84618 Mouse

Entrez Gene: 363274 Rat

Omim: 613858 Human

SwissProt: P0CW18 Human

SwissProt: F2YMG0 Mouse

Unigene: 570310 Human



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