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Rabbit Anti-NRSN2 antibody
Rabbit Anti-NRSN2 antibody
C20orf98; Neurensin 2; Neurensin-2; NRSN 2; NRSN2; NRSN2_HUMAN.
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  • NO.:SL19353R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Dog,Pig,Cow,Sheep,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name NRSN2
Chinese Name 神经囊泡膜蛋白2抗体
Alias C20orf98; Neurensin 2; Neurensin-2; NRSN 2; NRSN2; NRSN2_HUMAN.  
Research Area Cell biology  Neurobiology  Signal transduction  The cell membrane蛋白  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Dog, Pig, Cow, Sheep, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 22kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human NRSN2: 121-204/204 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Neurensin-2 is a 204 amino acid multi-pass membrane protein belonging to the VMP family that may be involved in the transport and maintenance of vesicles. Expressed in brain, Neurensin-2 localizes to cell bodies of hippocampus, diagonal band, amygdaloid nucleus, and habenula nucleus, and is a potential tumor suppressor gene and candidate biomarker for long-term survival in patients with hepatocellular carcinoma (HCC). The gene encoding Neurensin-2 maps to human chromosome 20, which comprises approximately 2% of the human genome, contains nearly 63 million bases and encodes over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

Function:
May play a role in maintenance and/or transport of vesicles.

Subcellular Location:
Membrane.

Similarity:
Belongs to the VMP family.

SWISS:
Q9GZP1

Gene ID:
80023

Database links:

Entrez Gene: 80023 Human

Omim: 610666 Human

SwissProt: Q9GZP1 Human

Unigene: 416024 Human



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