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Rabbit Anti-NRIP2 antibody
Rabbit Anti-NRIP2 antibody
DKFZp761G1913;; Neuronal interacting factor X 1; Nix1; Nrip2; NRIP2_HUMAN; Nuclear receptor interacting protein 2; Nuclear receptor-interacting protein 2.
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  • NO.:SL19349R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Product Name NRIP2
Chinese Name 核受体相互作用蛋白2抗体
Alias DKFZp761G1913;; Neuronal interacting factor X 1; Nix1; Nrip2; NRIP2_HUMAN; Nuclear receptor interacting protein 2; Nuclear receptor-interacting protein 2.  
Research Area Cell biology  Chromatin and nuclear signals  transcriptional regulatory factor  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 31kDa
Cellular localization The nucleus 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human NRIP2: 41-140/281 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail NRIP2 is a 281 amino acid nuclear protein that down-regulates transcriptional activation by nuclear receptors such as ROR∫. The gene encoding NRIP2 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.

Function:
Down-regulates transcriptional activation by nuclear receptors such as NR1F2.

Subunit:
Interacts with NR1F2, RARA and THRB in a ligand-dependent manner.

Subcellular Location:
Nucleus.

SWISS:
Q9BQI9

Gene ID:
83714

Database links:

Entrez Gene: 83714 Human

Entrez Gene: 60345 Mouse

SwissProt: Q9BQI9 Human

SwissProt: Q9JHR9 Mouse

Unigene: 530816 Human

Unigene: 269883 Mouse



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