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Product Name NRIP2 Chinese Name 核受体相互作用蛋白2抗体 Alias DKFZp761G1913;; Neuronal interacting factor X 1; Nix1; Nrip2; NRIP2_HUMAN; Nuclear receptor interacting protein 2; Nuclear receptor-interacting protein 2. Research Area Cell biology Chromatin and nuclear signals transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 31kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NRIP2: 41-140/281 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail NRIP2 is a 281 amino acid nuclear protein that down-regulates transcriptional activation by nuclear receptors such as ROR∫. The gene encoding NRIP2 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
Function:
Down-regulates transcriptional activation by nuclear receptors such as NR1F2.
Subunit:
Interacts with NR1F2, RARA and THRB in a ligand-dependent manner.
Subcellular Location:
Nucleus.
SWISS:
Q9BQI9
Gene ID:
83714
Database links:Entrez Gene: 83714 Human
Entrez Gene: 60345 Mouse
SwissProt: Q9BQI9 Human
SwissProt: Q9JHR9 Mouse
Unigene: 530816 Human
Unigene: 269883 Mouse
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