Product Name	WNT9A
Chinese Name	信号通路Wnt9a抗体
Alias	wingless-type MMTV integration site 9A; MGC124412; Protein Wnt 9b precursor; Wingless type MMTV integration site 9B; Wingless type MMTV integration site family member 15; Wingless type MMTV integration site family member 9B; Wnt 14b; Wnt-15; Wnt14b; Wnt15; Wnt9b wingless type MMTV integration site family member 9B; WNT14; WNT9A_HUMAN.
Research Area	Tumour  immunology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Pig, Cow, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	37kDa
Cellular localization	Extracellular matrix Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human WNT9A: 21-120/365
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Wnt9b is a member of the WNT family and is a ligand for members of the frizzled family of seven transmembrane receptors. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. Wnt9b is expressed in the inductive epithelia and is essential for the development of mesonephric and metanephric tubules and caudal extension of the Müllerian duct. Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. The gene is clustered with WNT3, another family member, in the chromosome 17q21 region. Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). Subcellular Location: Secreted, extracellular space, extracellular matrix. Tissue Specificity: Expressed in adult brain, lung, skeletal muscle, heart, and 17-day embryo. Similarity: Belongs to the Wnt family. SWISS: O14904 Gene ID: 7483 Database links: Entrez Gene: 7483 Human Entrez Gene: 216795 Mouse Entrez Gene: 287357 Rat Omim: 602863 Human SwissProt: O14904 Human SwissProt: Q8R5M2 Mouse Unigene: 149504 Human Unigene: 218794 Mouse Unigene: 40411 Rat
Product Picture	Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-WNT9A Polyclonal Antibody, Unconjugated(SL1933R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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