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Product Name NOM1 Chinese Name 核仁结构域蛋白NOM1抗体 Alias C7orf3; FLJ16401; NOM1; NOM1_HUMAN; Nucleolar MIF4G domain-containing protein 1; SGD1; SGD1 homolog. Research Area Cell biology Signal transduction Kinases and Phosphatases Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Rabbit, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 96kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NOM1: 31-130/860 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box RNA helicases (see EIF4A1; MIM 602641) (Simmons et al., 2005 [PubMed 15715967]).[supplied by OMIM, Mar 2008]
Function:
Plays a role in targeting PPP1CA to the nucleolus.
Subcellular Location:
Nucleus > nucleolus.
Tissue Specificity:
Expressed in heart and skeletal muscle.
Similarity:
Belongs to the CWC22 family.
Contains 1 MI domain.
Contains 1 MIF4G domain.
SWISS:
Q5C9Z4
Gene ID:
64434
Database links:Entrez Gene: 64434 Human
Omim: 611269 Human
SwissProt: Q5C9Z4 Human
Unigene: 15825 Human
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