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Product Name DCUN1D3 Chinese Name DCN1样蛋白3抗体 Alias 44M2.4; DCN1 defective in cullin neddylation 1 domain containing 3 (S. cerevisiae); DCN1 defective in cullin neddylation 1 domain containing 3; DCN1 like protein 3; DCN1-like protein 3; DCNL3_HUMAN; DCUN1 domain containing protein 3; DCUN1 domain-containing protein 3; dcun1d3; Defective in cullin neddylation protein 1 like protein 3; Defective in cullin neddylation protein 1-like protein 3; DKFZp686O0290; FLJ41725; MGC48972. Research Area Cell biology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 34kDa Cellular localization The nucleus The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human DCUN1D3: 21-120/304 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Dcun1D3 is a 304 amino acid protein that contains one Dcun1 domain. The Dcun1 domain is an approximately 190 residue module that is thought to have the features of a basic helix-loop-helix leucine zipper domain, a domain commonly found in transcription factors. It has been suggested that Dcun1D3 may be involved in cell cycle progression and cell growth. The gene that encodes Dcun1D3 maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. Chromosome 16 houses the CREBBP gene that encodes a critical CREB binding protein that is responsible for the Rubinstein-Taybi syndrome, a rare disorder characterized by mental retardation and predisposition to tumor growth and white blood cell neoplasias.
Subcellular Location:
Contains 1 DCUN1 domain.
SWISS:
Q8IWE4
Gene ID:
123879
Database links:Entrez Gene: 123879 Human
Entrez Gene: 233805 Mouse
SwissProt: Q8IWE4 Human
SwissProt: Q8K0V2 Mouse
Unigene: 101007 Human
Unigene: 31539 Mouse
Unigene: 211721 Rat
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