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Product Name NMES1 Chinese Name 食道癌相关基因NMES1抗体 Alias C15orf48; FLJ22645; FOAP-11; MGC32925; NMES1; NMES1_HUMAN; Normal mucosa of esophagus-specific gene 1 protein; Protein FOAP-11. Research Area Tumour Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 10kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NMES1: 31-83/83 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene was first identified in a study of human esophageal squamous cell carcinoma tissues. Levels of both the message and protein are reduced in carcinoma samples. In adult human tissues, this gene is expressed in the the esophagus, stomach, small intestine, colon and placenta. Alternatively spliced transcript variants that encode the same protein have been identified. [provided by RefSeq, Jun 2012]
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed mainly in stomach, placenta, small intestine and colon, as well as in normal mucosa of esophagus. Down-regulated in esophageal squamous cell carcinoma.
Similarity:
Belongs to the complex I NDUFA4 subunit family.
SWISS:
Q9C002
Gene ID:
84419
Database links:Entrez Gene: 84419 Human
Entrez Gene: 433470 Mouse
Omim: 608409 Human
SwissProt: Q9C002 Human
SwissProt: Q810Q5 Mouse
Unigene: 112242 Human
Product Picture Paraformaldehyde-fixed, paraffin embedded (Rat intestine); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NMES1) Polyclonal Antibody, Unconjugated (SL19295R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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