Product Name	phospho-NMDAR2A (Ser1232)
Chinese Name	磷酸化谷氨酸受体1抗体
Alias	NMDAR2A (phospho S1232); p-NMDAR2A (phospho S1232); GRIN2B; Glutamate [NMDA] receptor subunit epsilon 1; Glutamate [NMDA] receptor subunit epsilon 2; Glutamate [NMDA] receptor subunit epsilon-1; Glutamate [NMDA] receptor subunit epsilon-2; GRIN2A; hNR2A; hNR3; N methyl D aspartate receptor subtype 2A; N methyl D aspartate receptor subtype 2B; N-methyl D-aspartate receptor subtype 2A; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; NMDAR2A; NMDAR2B; NMDE2_HUMAN; NR2A; NR2B; NR3.
Product Type	Phosphorylated anti
Research Area	Cell biology  Neurobiology  Signal transduction  The cell membrane蛋白
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Horse, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	163kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated Synthesised phosphopeptide derived from human NMDAR2A around the phosphorylation site of Ser1232: MR(p-S)PF
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] Function: NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits. Subcellular Location: Cell membrane. Cell junction > synapse > postsynaptic cell membrane. Similarity: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2A/GRIN2A subfamily. SWISS: Q12879 Gene ID: 2903 Database links: Entrez Gene: 2903 Human Entrez Gene: 14811 Mouse Entrez Gene: 24409 Rat Omim: 138253 Human SwissProt: Q12879 Human SwissProt: P35436 Mouse SwissProt: Q00959 Rat Unigene: 411472 Human Unigene: 2953 Mouse Unigene: 9710 Rat

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