Product Name	NBEAL1
Chinese Name	NBEAL1蛋白抗体
Alias	neurobeachin-like 1; A530083I02Rik; ALS2CR16; ALS2CR17; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 16; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 17; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein; Beach; FLJ26555; MGC164581; MGC168834; NBEAL 1; NBEAL1; Neurobeachin like protein 1; OTTHUMP00000205117.
Research Area	Tumour  Cell biology  immunology  Neurobiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	307 , 151kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human NBEAL1: 1251-1350/2694
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	NBEAL1 is a 2,694 amino acid protein that belongs to the WD repeat Neurobeachin family. While highly expressed in kidney, brain, prostate and testis, NBEAL1 is also found at low levels in peripheral blood leukocytes, small intestine, ovary and colon. NBEAL1 contains one BEACH domain and two WD repeats, and undergoes alternative splicing to produce two isoforms. The gene encoding NBEAL1 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome. Function: Neurobeachin-like 1 belongs to the WD repeat neurobeachin family. It contains 1 BEACH domain and 2 WD repeats. Neurobeachin-like 1 is highly expressed in brain, kidney, prostate and testis and weakly expressed in ovary, small intestine, colon and peripheral blood leukocytes. It may be correlative to several tumors, such as ovary serous adenocarcinoma and metastasis mammary gland carcinoma breast. Tissue Specificity: Highly expressed in brain, kidney, prostate and testis. Weakly expressed in ovary, small intestine, colon and peripheral blood leukocytes. May be correlative to several tumors, such as ovary serous adenocarcinoma and metastasis mammary gland carcinoma breast. Similarity: Belongs to the WD repeat neurobeachin family. Contains 1 BEACH domain. Contains 1 BEACH-type PH domain. Contains 2 WD repeats. SWISS: Q6ZS30 Gene ID: 65065 Database links: Entrez Gene: 65065 Human Omim: 609816 Human SwissProt: Q6ZS30 Human

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