Product Name	ZFR
Chinese Name	锌指RNABinding protein抗体
Alias	FLJ41312; hZFR; M phase phosphoprotein homolog; M-phase phosphoprotein homolog; zfr; ZFR_HUMAN; zinc finger RNA binding protein; Zinc finger RNA-binding protein.
Research Area	Tumour  Apoptosis  transcriptional regulatory factor  Binding protein  Zinc finger protein  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	117kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ZFR: 271-370/1074
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	ZFR is 1,074 amino acid RNA-binding protein. In human, ZFR is expressed in lung, liver, lymphocytes, heart, pancreas, kidney and placenta, and regulates postimplantation and gastrulation stages of development. Murine ZFR is observed in testis, ovary and brain. With elevated levels of expression during meiosis, ZFR associates with chromosome foci in meiotic cells. ZFR contains 1 DZF domain and localizes in the somatodendritic compartment of hippocampal neurons and colocalizes with STAU2 in cytosolic RNA granules. Knockout of ZFR in mouse embryo prevents the development of some embryonic structures leads to an increase in programmed cell death with a decrease in mitotic index. Function: Involved in postimplantation and gastrulation stages of development. Involved in the nucleocytoplasmic shuttling of STAU2. Binds to DNA and RNA. Subcellular Location: Nucleus. Cytoplasm. Cytoplasmic granule. Chromosome. Associated with chromosome foci in meiotic cells. Localizes in somatodendritic compartment of primary hippocampal neurons. Colocalizes with STAU2 in several cytosolic RNA granules. Tissue Specificity: Expressed in lung, liver, lymphocytes, heart, pancreas, placenta, brain and kidney. Similarity: Contains 1 DZF domain. SWISS: Q96KR1 Gene ID: 51663 Database links: Entrez Gene: 51663 Human Entrez Gene: 22763 Mouse Entrez Gene: 365703 Rat Entrez Gene: 321659 Zebrafish SwissProt: Q96KR1 Human SwissProt: O88532 Mouse SwissProt: Q562A2 Rat SwissProt: Q6PCR6 Zebrafish Unigene: 435231 Human Unigene: 273496 Mouse Unigene: 11634 Rat Unigene: 26724 Zebrafish
Product Picture	Sample: Lane 1: Siha (Human) Cell Lysate at 30 ug Lane 2: HL60 (Human) Cell Lysate at 30 ug Lane 3: K562 (Human) Cell Lysate at 30 ug Lane 4: Hela (Human) Cell Lysate at 30 ug Primary: Anti-ZFR (SL19137R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 117 kD Observed band size: 117 kD

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