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Rabbit Anti-MUPCDH antibody
Rabbit Anti-MUPCDH antibody
Cadherin-related family member 5; Cdhr5; CDHR5_HUMAN; FLJ 20219; FLJ20219; MU-PCDH; Mu-protocadherin; MUCDHL; MUCDHL-ALT; MUCDHL-FL; Mucin and cadherin-like protein; mucin-like protocadherin.
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Details

Product Name MUPCDH
Chinese Name 钙粘蛋白相关家庭成员5/μ-protocadherin抗体
Alias Cadherin-related family member 5; Cdhr5; CDHR5_HUMAN; FLJ 20219; FLJ20219; MU-PCDH; Mu-protocadherin; MUCDHL; MUCDHL-ALT; MUCDHL-FL; Mucin and cadherin-like protein; mucin-like protocadherin.  
Research Area Cell biology  Signal transduction  Cell adhesion molecule  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, )
Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 85kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human MUPCDH: 161-260/845 <Extracellular>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jan 2010]

Function:
Acts as a calcium-dependent cell adhesion protein.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Highest expression in kidney, liver, colon and small intestine. In kidney, expressed apically along brush border of proximal convoluted tubule but not in cortical collecting ducts. Isoform 1 is expressed primarily in adult small intestine and colon. Isoform 2 is highly expressed in fetal liver.

Post-translational modifications:
N- and O-glycosylated.

Similarity:
Contains 4 cadherin domains.

SWISS:
Q9HBB8

Gene ID:
53841

Database links:

Entrez Gene: 53841 Human

Entrez Gene: 101138146 Gorilla

Entrez Gene: 100410617 Marmoset (common)

Entrez Gene: 100461892 Orangutan

Omim: 606839 Human

SwissProt: Q9HBB8 Human

Unigene: 165619 Human



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