Product Name	Myosin IXA
Chinese Name	肌球蛋白9A抗体
Alias	4732465J09Rik; C130068I12Rik; C230003M11; FLJ11061; FLJ13244; MGC71859; Myo9a; MYO9A variant protein; MYO9A_HUMAN; Myosin-IXa; MYR7; Unconventional myosin 9a; Unconventional myosin-9a.
Research Area	Cell biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Horse, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	293kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Myosin IXA: 711-810/2548
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with Bardet-Biedl Syndrome. [provided by RefSeq, Dec 2011] Function: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho activity in neurons, has a role in the regulation of neuronal morphology and function. Subcellular Location: Membrane. Tissue Specificity: Found to be expressed in testis and placenta, and at lower levels in all the examined tissues with the exception of liver. Isoform 5 was found in leukocytes but not in brain, retina or testis. Similarity: Contains 5 IQ domains. Contains 2 myosin head-like domains. Contains 2 phorbol-ester/DAG-type zinc fingers. Contains 1 Ras-associating domain. Contains 1 Rho-GAP domain. SWISS: B2RTY4 Gene ID: 4649 Database links: Entrez Gene: 4649 Human Entrez Gene: 270163 Mouse Entrez Gene: 171296 Rat Omim: 604875 Human SwissProt: B2RTY4 Human SwissProt: Q8C170 Mouse SwissProt: Q9Z1N3 Rat Unigene: 546268 Human Unigene: 249545 Mouse Unigene: 88901 Rat

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