Product Name	MED12L
Chinese Name	甲状腺激素受体相关蛋白复合物230样蛋白抗体
Alias	MD12L_HUMAN; MED12L; Mediator complex subunit 12-like protein; Mediator of RNA polymerase II transcription subunit 12-like protein; NOPAR; Thyroid hormone receptor-associated-like protein; TNRC11L; TRALP; TRALPUSH; Trinucleotide repeat-containing gene 11 protein-like.
Research Area	Cell biology  transcriptional regulatory factor  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	240kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MED12L: 601-700/2145
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery. [provided by RefSeq, May 2010] Function: May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Subunit: Belongs to the Mediator complex subunit 12 family. Subcellular Location: Nucleus. Similarity: Belongs to the Mediator complex subunit 12 family. SWISS: Q86YW9 Gene ID: 116931 Database links: Entrez Gene: 116931 Human Omim: 611318 Human SwissProt: Q86YW9 Human Unigene: 58561 Human Unigene: 730822 Human

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