Product Name	MCTP1
Chinese Name	MCTP1蛋白抗体
Alias	2810465F10Rik; FLJ22344; MCTP 1; Multiple C2 and transmembrane domain containing protein 1; Multiple C2 domains transmembrane 1; Multiple C2 domains with two transmembrane regions 1; OTTMUSP00000031345; RGD1305199.
Research Area	Tumour  Cell biology  Signal transduction  Binding protein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	115kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MCTP1: 901-999/999
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	MCTP1 is a 999 amino acid multi-pass membrane protein that belongs to the MCTP family. Existing as five alternatively spliced isoforms, MCTP1 binds calcium via its C2 domains in the absence of phospholipids. The gene encoding MCTP1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. Function: MCTP1 binds calcium via the C2 domains in the absence of phospholipids. There are 5 named isoforms. Subcellular Location: Membrane; Multi-pass membrane protein. SWISS: Q6DN14 Gene ID: 79772 Database links: Entrez Gene: 79772 Human Entrez Gene: 78771 Mouse Entrez Gene: 309928 Rat SwissProt: Q6DN14 Human

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