Product Name	MCM9
Chinese Name	微小染色体维持缺陷蛋白9抗体
Alias	C6orf61 ; DNA replication licensing factor MCM9 ; hMCM9 ; MCMDC1 ; Mini-chromosome maintenance deficient 9 ; Mini-chromosome maintenance deficient domain-containing protein 1.
Research Area	Cell biology  immunology  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, )
Applications	IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	44, 127kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MCM9: 371-470/1143
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1. [provided by RefSeq, Nov 2010] Function: Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart. Subunit: Component of the MCM8-MCM9 complex, which forms a hexamer composed of MCM8 and MCM9. Subcellular Location: Nucleus Similarity: Belongs to the MCM family. Contains 1 MCM domain. SWISS: Q9NXL9 Gene ID: 254394 Database links: Entrez Gene: 254394 Human Entrez Gene: 361852 Rat Omim: 610098 Human SwissProt: Q9NXL9 Human

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