Product Name	Mannosidase II
Chinese Name	α-甘露糖苷酶2抗体
Alias	3-1; 6-alpha-mannosidase; Alpha mannosidase 2; alpha Mannosidase II; alpha Mannosidase II; Alpha-mannosidase 2; AMAN II; Golgi alpha mannosidase II; Golgi alpha-mannosidase II; Golgi integral membrane protein 7; GOLIM7; MA2A1_HUMAN; MAN II; MAN2A1; MANA 2; MANA2; MANII; Mann II; Mann II; Mannosidase alpha class 2A member 1; Mannosidase Two; Mannosidase Two; Mannosidase, alpha type II; Mannosidase, alpha, II; Mannosyl oligosaccharide 1 3 1 6 alpha mannosidase; Mannosyl oligosaccharide 1,3 1,6 alpha mannosidase; Mannosyl oligosaccharide 13 16 alpha mannosidase; Mannosyl-oligosaccharide 1.
Research Area	Tumour  Cell biology  immunology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	131kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Mannosidase II: 351-450/1144
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus. [provided by RefSeq, Dec 2013] Function: Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway. Subunit: Homodimer; disulfide-linked Subcellular Location: Golgi apparatus membrane; Single-pass type II membrane protein Similarity: Belongs to the glycosyl hydrolase 38 family. SWISS: Q16706 Gene ID: 4124 Database links: Entrez Gene: 4124 Human Omim: 154582 Human SwissProt: Q16706 Human Unigene: 432822 Human

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