Product Name	MAN2A2
Chinese Name	α-甘露糖苷酶2x抗体
Alias	3-1; 6-alpha-mannosidase; Alpha-mannosidase 2x; Alpha-mannosidase IIx; MA2A2_HUMAN; MAN IIx; MAN2A2; MANA2X; Mannosidase alpha class 2A member 2; Mannosyl-oligosaccharide 1; Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase; MX.
Research Area	Cell biology  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	131kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MAN2A2: 1-100/1150
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	MAN2A2 is a single-pass type II membrane protein that localizes to the cisternae of the golgi and is involved in protein modification pathways. More specifically, MAN2A1 uses zinc as a cofactor to catalyze the first committed step in the formation of N-glycans, namely the hydrolysis of the terminal alpha-D-mannose residues in the oligosaccharide Man5(GlcNAc)3. Function: Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway. Subcellular Location: Golgi apparatus membrane. Similarity: Belongs to the glycosyl hydrolase 38 family. SWISS: P49641 Gene ID: 4122 Database links: Entrez Gene: 4122 Human Entrez Gene: 140481 Mouse Omim: 600988 Human SwissProt: P49641 Human SwissProt: Q8BRK9 Mouse Unigene: 116459 Human Unigene: 269245 Mouse
Product Picture	Sample: LOVO(Human) Cell Lysate at 30 ug FHC(Human) Cell Lysate at 30 ug Primary: Anti-MAN2A2 (SL18646R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 131 kD Observed band size: 131 kD

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