Product Name	MAMDC2
Chinese Name	MAMDC2蛋白抗体
Alias	MAM domain-containing protein 2; MAM domain-containing proteoglycan; MAMC2_HUMAN; Mamcan; Mamdc2.
Research Area	Cell biology  Developmental biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	75kDa
Cellular localization	Extracellular matrix Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MAMDC2: 601-686/686
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	MAMDC2 is a 686 amino acid secreted protein that localizes to extracellular matrix. Containing four MAM domains and existing as two alternatively spliced isoforms, MAMDC2 is encoded by a gene located on human chromosome 9q21.11. Chromosome 9 consists of about 145 million bases, 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, Familial dysautonomia and certain leukemias are also associated with chromosome 9. Subcellular Location: Secreted > extracellular space > extracellular matrix. Post-translational modifications: O-glycosylated. Similarity: Contains 4 MAM domains. SWISS: Q7Z304 Gene ID: 256691 Database links: Entrez Gene: 256691 Human Omim: 612879 Human SwissProt: Q7Z304 Human Unigene: 547172 Human

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