Product Name	MAK10
Chinese Name	胚胎生长相关蛋白MAK10抗体
Alias	bA379P1.1; Embryonic growth-associated protein homolog; FLJ21613; FLJ22643; N(alpha)-acetyltransferase 35, NatC auxiliary subunit; N-alpha-acetyltransferase 35; N-alpha-acetyltransferase 35, NatC auxiliary subunit; NAA35; NAA35_HUMAN; NatC auxiliary subunit; Protein MAK10 homolog; RP11-379P1.1.
Research Area	Cell biology  immunology  Developmental biology  Neurobiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	84kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MAK10: 151-250/725
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	MAK10 is a 725 amino acid cytoplasmic protein that regulates proliferation of smooth muscle cells. A member of the MAK10 family, MAK10 exists as a component of the N-terminal acetyltransferase C (NatC) complex along with LSmD1 and NAT-12. The gene encoding MAK10 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Function: Regulates proliferation of smooth muscle cells (By similarity). Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues. Subcellular Location: Cytoplasm. Similarity: Belongs to the MAK10 family. SWISS: Q5VZE5 Gene ID: 60560 Database links: Entrez Gene: 60560 Human Entrez Gene: 78689 Mouse Entrez Gene: 64472 Rat SwissProt: Q5VZE5 Human SwissProt: Q6PHQ8 Mouse SwissProt: Q6DKG0 Rat Unigene: 436098 Human Unigene: 253902 Mouse Unigene: 73698 Rat

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