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Rabbit Anti-LPHN3 antibody
Rabbit Anti-LPHN3 antibody
Calcium independent alpha latrotoxin receptor 3; Calcium-independent alpha-latrotoxin receptor 3; CIRL 3; CIRL-3; CIRL3; cl3 latrotoxin receptor; KIAA0768; Latrophilin 3; Latrophilin homolog 3 (cow); Latrophilin homolog 3; Latrophilin-3; Latrophilin3; LEC
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  • NO.:SL18350R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,Monkey,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name LPHN3
Chinese Name 蛛毒素受体3抗体
Alias Calcium independent alpha latrotoxin receptor 3; Calcium-independent alpha-latrotoxin receptor 3; CIRL 3; CIRL-3; CIRL3; cl3 latrotoxin receptor; KIAA0768; Latrophilin 3; Latrophilin homolog 3 (cow); Latrophilin homolog 3; Latrophilin-3; Latrophilin3; LEC 3; LEC3; Lectomedin 3; Lectomedin-3; Lectomedin3; lph3; LPHN 3; Lphn3; LPHN3_HUMAN.  
Research Area Cell biology  Neurobiology  Signal transduction  G protein-coupled receptor  G protein signal  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Monkey, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 160kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human LPHN3: 1171-1270/1447 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008]

Subcellular Location:
Cell membrane.

Post-translational modifications:
Proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.

Similarity:
Belongs to the G-protein coupled receptor 2 family.
LN-TM7 subfamily.
Contains 1 GPS domain.
Contains 1 olfactomedin-like domain.
Contains 1 SUEL-type lectin domain.

SWISS:
Q9HAR2

Gene ID:
23284

Database links:

Entrez Gene: 23284 Human

Entrez Gene: 319387 Mouse

Entrez Gene: 170641 Rat

SwissProt: Q9HAR2 Human

SwissProt: Q80TS3 Mouse

SwissProt: Q9Z173 Rat

Unigene: 28391 Human

Unigene: 570770 Human

Unigene: 273631 Mouse

Unigene: 461016 Mouse

Unigene: 203386 Rat



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