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Product Name LPGAT1 Chinese Name 溶血磷脂酰甘油酰基转移酶1抗体 Alias Acyl CoA:lysophosphatidylglycerol acyltransferase 1; Acyl-CoA:lysophosphatidylglycerol acyltransferase 1; FAM34A; FAM34A1; Family with sequence similarity 34 member A; KIAA0205; LGAT1_HUMAN; Lpgat1; lysophosphatidylglycerol acyltransferase 1; NET8. literatures Specific References (1) | SL18347R has been referenced in 1 publications.[IF=3.115] Huiyuan Gong. et al. Upregulation of LPGAT1 Enhances Lung Adenocarcinoma Proliferation. FRONT BIOSCI-LANDMRK. 2023 May;28(5):89 WB ; Human.Research Area Cell biology immunology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Pig, ) Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 43kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human LPGAT1: 151-250/370 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Acyl-CoA:lysophosphatidylglycerol (LPG) acyltransferase catalyzes the reacylation of LPG to phosphatidylglycerol, a membrane phospholipid that is an important precursor for the synthesis of cardiolipin (Yang et al., 2004 [PubMed 15485873]).[supplied by OMIM, Mar 2008]
Function:
Lysophoshatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor.
Subcellular Location:
Endoplasmic reticulum membrane.
Tissue Specificity:
Highly expressed in liver and placenta. Also expressed in peripheral blood, lung, kidney and brain. Detected at lower levels in colon.
Similarity:
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
SWISS:
Q92604
Gene ID:
9926
Database links:
Entrez Gene: 9926 Human
Entrez Gene: 226856 Mouse
Omim: 610473 Human
SwissProt: Q92604 Human
SwissProt: Q91YX5 Mouse
Unigene: 725980 Human
Unigene: 277958 Mouse
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