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Product Name RNF192 Chinese Name Ring finger protein192抗体 Alias FLJ45273; LON peptidase N terminal domain and ring finger 2; LON peptidase N terminal domain and RING finger protein 2; LONRF 2; MGC126711; MGC126713; Neuroblastoma apoptosis related protease; RING finger protein 192; RNF 192; RNF192. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 84kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human RNF192: 601-700/745 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. LONRF2 is a 754 amino acid protein containing one LON domain, one RING-type zinc finger and six TPR repeats. Two isoforms of LONRF2 are produced by alternative splicing events. The gene encoding LONRF2 maps to human chromosome 2q11.2 and mouse chromosome 1 B.
Function:
LONRF2 contains one Lon domain, one RING type zinc finger and six TPR repeats. The function of LONRF2 is unknown. There are two named isoforms.
Similarity:
Contains 1 Lon domain. Contains 1 RING-type zinc finger. Contains 6 TPR repeats.
SWISS:
Q1L5Z9
Gene ID:
164832
Database links:
Entrez Gene: 164832 Human
Entrez Gene: 381338 Mouse
SwissProt: Q1L5Z9 Human
SwissProt: B2RT44 Mouse
Unigene: 21380 Human
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