Product Name	RNF192
Chinese Name	Ring finger protein192抗体
Alias	FLJ45273; LON peptidase N terminal domain and ring finger 2; LON peptidase N terminal domain and RING finger protein 2; LONRF 2; MGC126711; MGC126713; Neuroblastoma apoptosis related protease; RING finger protein 192; RNF 192; RNF192.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	84kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RNF192: 601-700/745
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. LONRF2 is a 754 amino acid protein containing one LON domain, one RING-type zinc finger and six TPR repeats. Two isoforms of LONRF2 are produced by alternative splicing events. The gene encoding LONRF2 maps to human chromosome 2q11.2 and mouse chromosome 1 B. Function: LONRF2 contains one Lon domain, one RING type zinc finger and six TPR repeats. The function of LONRF2 is unknown. There are two named isoforms. Similarity: Contains 1 Lon domain. Contains 1 RING-type zinc finger. Contains 6 TPR repeats. SWISS: Q1L5Z9 Gene ID: 164832 Database links: Entrez Gene: 481336 Dog Entrez Gene: 164832 Human Entrez Gene: 381338 Mouse Entrez Gene: 301361 Rat SwissProt: Q1L5Z9 Human SwissProt: B2RT44 Mouse Unigene: 21380 Human

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