Product Name	LMO1
Chinese Name	TlymphocyteTransporter1抗体
Alias	Cysteine rich protein TTG 1; Cysteine rich protein TTG1; LIM domain only 1; LIM domain only protein 1; LMO 1; MGC116692; RBTN 1; RBTN1; RHOM 1; RHOM1; Rhombotin 1; Rhombotin1; T cell translocation protein 1; TTG 1; TTG1.
Research Area	Cell biology  Transporter  lymphocyte  t-lymphocyte  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, Chicken, Pig, Cow, Rabbit, Zebrafish, Guinea Pig, Monkey, Cat, )
Applications	WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	18kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LMO1: 1-80/156
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2012] Function: May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors. Subcellular Location: Nuclear Tissue Specificity: Expressed mainly in the central nervous. Low level of expression in other tissues including thymus. DISEASE: A chromosomal aberration involving LMO1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p15;q11) with TCRD. Similarity: Contains 2 LIM zinc-binding domains. SWISS: P25800 Gene ID: 4004 Database links: Entrez Gene: 27152 Cow Entrez Gene: 4004 Human Entrez Gene: 109594 Mouse Entrez Gene: 245979 Rat Entrez Gene: 280646 Zebrafish Omim: 186921 Human SwissProt: Q0P5B3 Cow SwissProt: P25800 Human SwissProt: Q924W9 Mouse SwissProt: Q8JFQ2 Zebrafish Unigene: 654426 Human
Product Picture	Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LMO1) Polyclonal Antibody, Unconjugated (SL18313R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LMO1) Polyclonal Antibody, Unconjugated (SL18313R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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