TEL: +86 571 56623320 EMAIL: [email protected]
Product Name LMF1 Chinese Name 脂肪酶成熟因子1抗体 Alias AW822050; C16orf26; cld; FLJ12681; FLJ22302; HMFN1876; JFP11; Lipase maturation factor 1; LMF1; LMF1_HUMAN; RGD1310180; TMEM112; TMEM112A; Transmembrane protein 112. Research Area Tumour Cell biology immunology The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 65kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human LMF1: 11-120/567 <Cytoplasmic> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene resides in the endoplasmic reticulum, and is involved in the maturation and transport of lipoprotein lipase through the secretory pathway. Mutations in this gene are associated with combined lipase deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2010]
Function:
Involved in the maturation of specific proteins in the endoplasmic reticulum. Required for maturation and transport of active lipoprotein lipase (LPL) through the secretory pathway.
Subcellular Location:
Endoplasmic reticulum membrane.
DISEASE:
Defects in LMF1 are the cause of combined lipase deficiency (CLD) [MIM:246650]. CLD is characterized by repeated episodes of pancreatitis, tuberous xanthomas and lipodystrophy and is caused by deficiency of both lipoprotein lipase (LPL) and hepatic triglyceride lipase (HTGL).
Similarity:
Belongs to the lipase maturation factor family.
SWISS:
Q96S06
Gene ID:
64788
Database links:Entrez Gene: 64788 Human
Omim: 611761 Human
SwissProt: Q96S06 Human
Unigene: 71912 Human
Scan Wechat Qrcode
Scan Whatsapp Qrcode