Product Name	LMAN2L/VIPL
Chinese Name	凝集素甘露糖Binding protein2样蛋白抗体
Alias	DKFZp564L2423; Lectin mannose-binding 2-like; lectin, mannose binding 2 like; LMA2L_HUMAN; LMAN2 like protein; LMAN2-like protein; LMAN2L; MGC11139; VIP36 like protein [Precursor]; VIP36-like protein; VIPL.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	38kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LMAN2L/VIPL: 45-140/348
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Lectin mannose-binding 1, also designated vesicular integral-membrane protein (VIP36), and lectin mannose-binding 2, also designated ERGIC-53, comprise a family of membrane bound, ubiquitously expressed proteins involved in the selective transport of newly synthesized glycoproteins from the endoplasmic reticulum to the ER-Golgi intermediate compartment. VIPL (VIP36-like protein), also known as LMAN2L (lectin, mannose-binding 2-like), is a 348 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum and Golgi apparatus. Containing one L-type lectin-like domain, VIPL is highly expressed in skeletal muscle and kidney, and is found at intermediate levels in heart, liver and placenta, and low levels in brain, thymus, spleen, small intestine and lung. VIPL is suggested to be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. VIPL may function as a regulator of ERGIC-53. VIPL exists a two alternatively spliced isoforms. Function: May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53. Subcellular Location: Endoplasmic reticulum membrane. Golgi apparatus membrane. Predominantly found in the endoplasmic reticulum. Partly found in the Golgi. Tissue Specificity: Expressed in numerous tissues. Highest expression in skeletal muscle and kidney, intermediate levels in heart, liver and placenta, low levels in brain, thymus, spleen, small intestine and lung. Similarity: Contains 1 L-type lectin-like domain. SWISS: Q9H0V9 Gene ID: 81562 Database links: Entrez Gene: 81562 Human Entrez Gene: 214895 Mouse Entrez Gene: 301343 Rat Omim: 609552 Human SwissProt: Q9H0V9 Human SwissProt: P59481 Mouse Unigene: 655743 Human Unigene: 287854 Mouse
Product Picture	Sample: Muscle (Mouse) Lysate at 40 ug Primary: Anti-LMAN2L/VIPL (SL18307R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 38 kD Observed band size: 38 kD

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