Product Name	LIPN/Lipase N
Chinese Name	脂肪水解酶LIPN抗体
Alias	bA186O14.3; LI4; Lipase member N; Lipase, family member N; Lipase-like abhydrolase domain-containing protein 4; LIPL4; Lipn; LIPN_HUMAN.
Research Area	Cell biology  Signal transduction  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Horse, )
Applications	IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	44kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LIPN/Lipase N: 101-200/398
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The gene encodes a lipase that is highly expressed in granular keratinocytes in the epidermis, and plays a role in the differentiation of keratinocytes. Mutations in this gene are associated with lamellar ichthyosis type 4. [provided by RefSeq, Dec 2011] Function: Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers. Subcellular Location: Secreted. Tissue Specificity: Exclusively expressed in the epidermis within the granular keratinocytes. Similarity: Belongs to the AB hydrolase superfamily. Lipase family. SWISS: Q5VXI9 Gene ID: 643418 Database links: Entrez Gene: 643418 Human Omim: 613924 Human SwissProt: Q5VXI9 Human Unigene: 632091 Human

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