Product Name	LIMKAIN B1
Chinese Name	减数分裂阻滞蛋白1抗体
Alias	KIAA0430; Limkain-b1; LKAP; MARF1_HUMAN; MARF1; Meiosis arrest female 1; Meiosis arrest female protein 1; PPP1R34; Protein phosphatase 1, regulatory subunit 34.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	193kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LIMKAIN B1: 701-800/1742
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a putative peroxisomal protein that appears to be conserved across Euteleostomi. In humans, it may be autoantigenic. [provided by RefSeq, Jul 2010] Function: Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks (By similarity). Subunit: Interacts with LIMK2. Subcellular Location: Peroxisome. Similarity: Contains 1 RRM (RNA recognition motif) domain. SWISS: Q9Y4F3 Gene ID: 9665 Database links: Entrez Gene: 9665 Human Entrez Gene: 223989 Mouse Omim: 614593 Human SwissProt: Q9Y4F3 Human SwissProt: Q8BJ34 Mouse Unigene: 173524 Human Unigene: 85442 Mouse

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