Product Name	LCE6A
Chinese Name	晚期角质化包膜蛋白抗体
Alias	C1orf44; Late cornified envelope 6A; Late cornified envelope protein 6A; LCE6A; LCE6A_HUMAN.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	9kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LCE6A: 21-80/80
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	LCE6A is an 80 amino acid protein belonging to the LCE family. The LCE gene cluster within the epidermal differentiation complex on human chromosome 1 and mouse chromosome 3 contains multiple conserved genes encoding stratum-corneum proteins. Within the LCE cluster, genes form “groups” based on chromosomal position and protein homology. LCE6A is a precursor of the cornified envelope of the stratum corneum and belongs to the LCE cluster present on human chromosome 1q21. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1, including Stickler syndrome, Parkinsons and Gaucher disease. Function: Precursors of the cornified envelope of the stratum corneum. Similarity: Belongs to the LCE family. SWISS: A0A183 Gene ID: 448835 Database links: Entrez Gene: 448835 Human SwissProt: A0A183 Human Unigene: 62927 Human

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