Product Name	TNPO3
Chinese Name	Transporter3抗体
Alias	TNPO 3; Imp12; Importin 12; Importin-12; IPO12; MTR10A; TNPO 3; TNPO3; TNPO3_HUMAN; Transportin 3; Transportin SR; Transportin-3; Transportin-SR; TRN SR; TRN-SR; TRN-SR2; TRNSR.
Research Area	Cell biology  immunology  Signal transduction  transcriptional regulatory factor  Lipoprotein  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Cow, Horse, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	104kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TNPO3: 821-923/923
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 2010] Function: Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins SFRS1 and SFRS2, by recognizing phosphorylated RS domains. Subunit: Interacts with phosphorylated SFRS1 and SFRS2. Interacts with NUP62 and RBM4. Subcellular Location: Cytoplasm. Nucleus. SWISS: Q9Y5L0 Gene ID: 23534 Database links: Entrez Gene: 23534 Human Entrez Gene: 320938 Mouse Omim: 610032 Human SwissProt: Q9Y5L0 Human SwissProt: Q6P2B1 Mouse Unigene: 193613 Human Unigene: 276381 Mouse Unigene: 304472 Mouse Unigene: 352219 Mouse Unigene: 424508 Mouse Unigene: 429470 Mouse Unigene: 439108 Mouse

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