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Product Name RELT/TNFRSF19L Chinese Name Tumour坏死因子受体超家族成员19L抗体 Alias Receptor expressed in lymphoid tissues; RELT; TNFRSF19L; Tumor necrosis factor receptor superfamily member 19L. Research Area Cell biology immunology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, ) Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 43kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human RELT/TNFRSF19L: 101-200/430 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
Function:
TNFRSF19L may be involved in T cell activation by mediation of the NF kappa B pathway.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Cytoplasm
Similarity:
Belongs to the RELT family.
Contains 1 TNFR-Cys repeat
SWISS:
Q969Z4
Gene ID:
84957
Database links:Entrez Gene: 84957 Human
Entrez Gene: 320100 Mouse
Omim: 611211 Human
SwissProt: Q969Z4 Human
SwissProt: Q8BX43 Mouse
Unigene: 533720 Human
Unigene: 40336 Mouse
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