Product Name	IGSF22
Chinese Name	免疫球蛋白超家族成员22抗体
Alias	Immunoglobulin superfamily member 22.
Research Area	Cell biology  immunology  The cell membrane受体
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Dog, Cat, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	100kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human IGSF22: 221-320/903
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	IGSF22 (immunoglobulin superfamily member 22) is a 903 amino acid protein that contains two fibronectin type-III domains and four Ig-like (immunoglobulin-like) domains, and is a member of the immunoglobulin superfamily. Members of this family of proteins usually localize to the cell membrane, and may act as receptors in immune response pathways. The gene encoding IGSF22 maps to human chromosome 11p15.1. Chromosome 11 houses over 1,400 genes, comprises nearly 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes. Similarity: Contains 2 fibronectin type-III domains. Contains 4 Ig-like (immunoglobulin-like) domains. SWISS: Q8N9C0 Gene ID: 283284 Database links: Entrez Gene: 283284 Human SwissProt: Q8N9C0 Human

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