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Rabbit Anti-phospho-IL13RA1 (Tyr405)antibody
Rabbit Anti-phospho-IL13RA1 (Tyr405)antibody
IL13 receptor alpha 1 (phospho Y405); p-IL13 receptor alpha 1 (phospho Y405);I13R1_HUMAN; Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19 (CT19); CD213a1;
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  • NO.:SL18135R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Human,Rat,Pig,Horse,Rabbit,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Product Name phospho-IL13RA1 (Tyr405)
Chinese Name 磷酸化白细胞介素13受体α1抗体
Alias IL13 receptor alpha 1 (phospho Y405); p-IL13 receptor alpha 1 (phospho Y405); I13R1_HUMAN; Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19 (CT19); CD213a1; IL13R, IL13RA; NR4; CT19; CD213A1; IL-13Ra;   
Product Type Phosphorylated anti 
Research Area Cell biology  Signal transduction  Kinases and Phosphatases  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Pig, Horse, Rabbit, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 42kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated Synthesised phosphopeptide derived from human IL13 receptor alpha 1 around the phosphorylation site of Tyr405: DI(p-Y)EK 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008]

Function:
Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.

Subcellular Location:
Membrane.

Tissue Specificity:
Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.

Similarity:
Belongs to the type I cytokine receptor family. Type 5 subfamily.

SWISS:
P78552

Gene ID:
3597

Database links:

Entrez Gene: 3597 Human

Entrez Gene: 16164 Mouse

Omim: 300119 Human

SwissProt: P78552 Human

SwissProt: O09030 Mouse

Unigene: 496646 Human

Unigene: 24208 Mouse



Product Picture
Sample:
Heart (Mouse) Lysate at 40 ug
Liver (Mouse) Lysate at 40 ug
Primary: Anti-p-IL13receptor alpha 1 (Tyr405) (SL18135R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 42 kD

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