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Product Name HYAL4 Chinese Name 透明质酸酶4抗体 Alias chondroitin sulfate hydrolase; CSHY; Hyal-4; Hyal4; HYAL4_HUMAN; Hyaluronidase-4; Hyaluronoglucosaminidase-4. Research Area Tumour Cell biology Signal transduction The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Pig, Cow, Horse, Rabbit, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 54kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human HYAL4: 151-250/481 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity. [provided by RefSeq, Jul 2008]
Function:
Endo-hyaluronidase that degrades hyaluronan to smaller oligosaccharide fragments. Has also chondroitase activity.
Subcellular Location:
Membrane.
Tissue Specificity:
Detected in placenta and skeletal muscle.
Similarity:
Belongs to the glycosyl hydrolase 56 family.
SWISS:
Q2M3T9
Gene ID:
23553
Database links:Entrez Gene: 23553 Human
Omim: 604510 Human
SwissProt: Q2M3T9 Human
Unigene: 28673 Human
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