Product Name	HVCN1
Chinese Name	氢离子电压门控Channel protein1抗体
Alias	HV 1; HV1; HVCN 1; HVCN1; HVCN1_HUMAN; Hydrogen voltage gated channel 1; Hydrogen voltage-gated channel 1; Voltage gated hydrogen channel 1; Voltage sensor domain only protein; Voltage sensor domain-only protein; Voltage-gated hydrogen channel 1; VSOP.
Research Area	Tumour  Cell biology  immunology  Signal transduction  lymphocyte  b-lymphocyte
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	32kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HVCN1: 201-273/273
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a voltage-gated protein channel protein expressed more highly in certain cells of the immune system. Phagocytic cells produce superoxide anions which require this channel protein, and in B cells this same process facilitates antibody production. This same channel protein, however, can also regulate functions in other cells including spermatozoa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] Function: Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis. Subcellular Location: Membrane. Tissue Specificity: Enriched in immune tissues, such as lymph nodes, B-lymphocytes, monocytes and spleen. Similarity: Belongs to the hydrogen channel family. SWISS: Q96D96 Gene ID: 84329 Database links: Entrez Gene: 84329 Human Entrez Gene: 74096 Mouse Omim: 611227 Human SwissProt: Q96D96 Human SwissProt: Q3U2S8 Mouse Unigene: 211511 Human Unigene: 334637 Human Unigene: 28804 Mouse

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