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Product Name HSZFP36/ZNF823 Chinese Name Zinc finger protein823抗体 Alias ZFP 36 for a zinc finger protein; Zinc finger protein 823; Zinc finger protein ZFP 36; ZNF823. Research Area Cell biology transcriptional regulatory factor Zinc finger protein Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 70kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human HSZFP36/ZNF823: 101-200/610 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HSZFP36, also known as ZNF823 (zinc finger protein 823) or ZFP36, is a 610 amino acid member of the Krüppel C2H2-type zinc-finger protein family and is thought be involved in transcriptional regulation. Localized to the nucleus, HSZFP36 contains one KRAB domain and 16 C2H2-type zinc fingers through which it may convey DNA, RNA and protein binding capabilities.
Function:
The cDNA sequence of HSZFP36 was generated by the Mammalian Gene Collection (MGC) Program Team.
Subcellular Location:
Nuclear
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 16 C2H2-type zinc fingers.
Contains 1 KRAB domain.
SWISS:
P16415
Gene ID:
55552
Database links:Entrez Gene: 55552 Human
SwissProt: P16415 Human
Unigene: 534052 Human
Unigene: 389856 Mouse
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