Product Name	HSPA7
Chinese Name	热休克蛋白70蛋白7抗体
Alias	Heat shock 70 kDa protein B; Heat shock 70kDa protein 7 (HSP70B); HSP70B; Putative heat shock 70 kDa protein 7.
Research Area	Cell biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	40kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HSPA7: 101-200/367
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent polypeptide chains across cellular membranes and the regulation of protein folding. HSPA7 (heat shock 70kDa protein 7), also known as HSP70B, is a 367 amino acid protein belonging to the heat shock protein 70 family, and like other HSP proteins, mediates protein folding within the cytosol, as well as within other organelles throughout the cell. The gene encoding HSPA7 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. Function: Heat shock 70kDa protein 7 may play a role in ATP binding as part of the stress response. Similarity: Belongs to the heat shock protein 70 family. SWISS: P48741 Gene ID: 3311 Database links: Entrez Gene: 3311 Human Omim: 140556 Human SwissProt: P48741 Human Unigene: 662180 Human

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