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Rabbit Anti-CNGA2  antibody
Rabbit Anti-CNGA2 antibody
CNCA; CNCA1; CNG2; FLJ46312; OCNC1; OCNCa; OCNCALPHA; olfactory cyclic nucleotide-gated ion channel alpha subunit; olfactory ion channel protein; Cyclic nucleotide-gated olfactory channel; Cyclic nucleotide-gated cation channel 2; Cyclic nucleotide-gated
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Details

Product Name CNGA2
Chinese Name 环核苷酸阳离子Channel proteinα2抗体
Alias CNCA; CNCA1; CNG2; FLJ46312; OCNC1; OCNCa; OCNCALPHA; olfactory cyclic nucleotide-gated ion channel alpha subunit; olfactory ion channel protein; Cyclic nucleotide-gated olfactory channel; Cyclic nucleotide-gated cation channel 2; Cyclic nucleotide-gated channel alpha-2; CNG channel alpha-2; CNG-2; Cyclic nucleotide-gated olfactory channel subunit OCNC1; CNGA2_HUMAN.  
Research Area Cardiovascular  Neurobiology  Channel protein  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Dog, Pig, Rabbit, )
Applications WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 73kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CNGA2 : 193-270/664 <Cytoplasmic>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail dorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. CNGA2 belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family and contains one cyclic nucleotide-binding domain. It may be involved in odorant signal transduction. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.

Function:
Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA2 subfamily.
Contains 1 cyclic nucleotide-binding domain.

SWISS:
Q16280

Gene ID:
1260

Database links:

Entrez Gene: 1260 Human

Entrez Gene: 12789 Mouse

Entrez Gene: 25411 Rat

Omim: 300338 Human

SwissProt: Q16280 Human

SwissProt: Q62398 Mouse

SwissProt: Q00195 Rat

Unigene: 447360 Human

Unigene: 5097 Mouse

Unigene: 10384 Rat



环核苷酸阳离子Channel proteinα2为阳离子通道结构蛋白。
Product Picture
Sample:
Kidney (Mouse) Lysate at 40 ug
Primary: Anti- CNGA2 (SL1785R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 73 kD
Observed band size: 73 kD

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