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Product Name MRPL24 Chinese Name Mitochondrion核糖体蛋白L24抗体 Alias 39S ribosomal protein L24, mitochondrial; FLJ20917; MGC22737; MGC9831; Mitochondrial ribosomal protein L24; MRP L18; MRP L24; MRPL 24; OTTHUMP00000038724; OTTHUMP00000038725; OTTHUMP00000038728. Research Area Cell biology transcriptional regulatory factor Cell type markers Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 24kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MRPL24: 10-100/216 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
Function:
MRPL24 is a mitochondrial ribosomal protein (MRP). Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. This is a 39S subunit protein.
Subcellular Location:
Mitochondrial
Similarity:
Belongs to the ribosomal protein L24P family; Contains 1 KOW domain.
SWISS:
Q96A35
Gene ID:
75590
Database links:Entrez Gene: 79590 Human
Entrez Gene: 67707 Mouse
Omim: 611836 Human
SwissProt: Q96A35 Human
SwissProt: Q9CQ06 Mouse
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