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Product Name MOGAT3 Chinese Name MOGAT3蛋白抗体 Alias 2 acylglycerol O acyltransferase 3; 2-acylglycerol O-acyltransferase 3; Acyl CoA:monoacylglycerol acyltransferase 3; Acyl coenzyme A:monoacylglycerol acyltransferase 3; Acyl-CoA:monoacylglycerol acyltransferase 3; DC 7; DC7; DGAT2L7; Diacylglycerol acyltransferase 2 like protein 7; Diacylglycerol acyltransferase 2-like protein 7; Diacylglycerol O acyltransferase candidate 7; Diacylglycerol O-acyltransferase candidate 7; hDC 7; hDC7; MGAT 3; MGAT3; MGC119203; MGC119204; MOGAT 3; MOGAT3; MOGT3_HUMAN; Monoacylglycerol O acyltransferase 3; Monoacylglycerol O-acyltransferase 3. Research Area Tumour Cell biology Signal transduction The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 39kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MOGAT3: 1-80/141 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM, Mar 2008]
Function:
Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes.
Subcellular Location:
Endoplasmic reticulum membrane.
Tissue Specificity:
Selectively expressed in the digestive system. Highly expressed in the ileum, and at lower level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and trachea. Expressed at very low level in liver.
Similarity:
Belongs to the diacylglycerol acyltransferase family.
SWISS:
Q86VF5
Gene ID:
346606
Database links:Entrez Gene: 346606 Human
Omim: 610184 Human
SwissProt: Q86VF5 Human
Unigene: 512217 Human
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