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Product Name MOBKL2A Chinese Name MOBKL2A蛋白抗体 Alias MOB-LAK; Mob1 homolog 2A; MOBKL2A; MOL2A_HUMAN; Mps one binder kinase activator-like 2A; Protein Mob3A。 Research Area Cell biology immunology Neurobiology Diabetes Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Dog, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 25kDa Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MOBKL2A: 61-160/217 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail MOBKL2A is a 217 amino acid protein that regulates kinase activity. A member of the MOB1/phocein family, MOBKL2A is encoded by a gene that maps to human chromosome 19. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc?receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19.
Function:
May regulate the activity of kinases.
Similarity:
Belongs to the MOB1/phocein family.
SWISS:
Q96BX8
Gene ID:
126308
Database links:Entrez Gene: 126308 Human
Entrez Gene: 208228 Mouse
SwissProt: Q96BX8 Human
SwissProt: Q8BSU7 Mouse
Unigene: 86912 Human
Product Picture Paraformaldehyde-fixed, paraffin embedded (rat brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MOBKL2A) Polyclonal Antibody, Unconjugated (SL17699R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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