Product Name	SPATA6
Chinese Name	精子发生相关蛋白6抗体
Alias	1700062C23Rik; AI790763; FLJ10007; Hash; KRP; Mash; RP23 402I22.1; spermatogenesis associated 6; SRF 1; SRF1.
Research Area	Cell biology  Developmental biology  Stem cells
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, )
Applications	IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	54kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SPATA6: 151-250/488
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	SPATA6 is a 488 amino acid secreted protein that may be involved in spermatid maturation or sperm function. SPATA6 is expressed during embryonic development and is localized in neural tube, somites and limb buds of mouse embryo. Existing as two isoforms produced by alternative splicing events, the gene encoding SPATA6 maps to mouse chromosome 4 and human chromosome 1. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. Function: SPATA6 belongs to the SPATA6 family. SPATA6 may play a role in spermatid maturation or sperm function. Subcellular Location: Secreted Similarity: Belongs to the SPATA6 family. SWISS: Q9NWH7 Gene ID: 54558 Database links: Entrez Gene: 54558 Human Entrez Gene: 67946 Mouse Entrez Gene: 171413 Rat Omim: 613947 Human SwissProt: Q9NWH7 Human SwissProt: Q3U6K5 Mouse SwissProt: Q99MU5 Rat

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