Product Name	SPATA5
Chinese Name	精子发生相关蛋白2抗体
Alias	AFG2; ATPase family gene 2 homolog; ATPase family protein 2 homolog; SPAF; Spermatogenesis associated 5; Spermatogenesis associated factor SPAF; Spermatogenesis-associated factor protein.
Research Area	Cell biology  Developmental biology  Stem cells
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	98kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SPATA5: 801-893/893
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	SPATA5 is an 893 amino acid protein that localizes to cytoplasm and mitochondrion, and may be involved in morphological and functional mitochondrial transformations during spermatogenesis. Existing as three alternatively spliced isoforms, SPATA5 belongs to the AAA ATPase family and the AFG2 subfamily. The gene that encodes SPATA5 consists of more than 396,000 bases and maps to human chromosome 4q28.1. Housing nearly 900 genes, chromosome 4 represents approximately 6% of the human genome and is associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Function: May be involved in morphological and functional mitochondrial transformations during spermatogenesis. Subcellular Location: Cytoplasmic and Mitochondrial Similarity: Belongs to the AAA ATPase family. AFG2 subfamily. SWISS: Q8NB90 Gene ID: 166378 Database links: Entrez Gene: 166378 Human Entrez Gene: 57815 Mouse Entrez Gene: 361935 Rat SwissProt: Q8NB90 Human SwissProt: Q3UMC0 Mouse

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