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Product Name SPATA2L Chinese Name 精子发生相关蛋白2样蛋白抗体 Alias C16orf76; chromosome 16 open reading frame 76; MGC26885; SPA2L_HUMAN; SPATA2 like protein; SPATA2-like protein; Spata2L; spermatogenesis associated 2 like; Spermatogenesis associated protein 2 like protein; Spermatogenesis-associated protein 2-like protein; tamo. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Cow, Sheep, ) Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 46kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SPATA2L: 101-200/424 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. The gene encoding SPATS2L maps to human locus 2q33.1.
Similarity:
Belongs to the SPATA2 family.
SWISS:
Q8IUW3
Gene ID:
124044
Database links:Entrez Gene: 124044 Human
SwissProt: Q8IUW3 Human
Unigene: 374556 Human
Unigene: 91547 Rat
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