Product Name	SPANXD/CT11.4
Chinese Name	癌/睾丸抗原11.4抗体
Alias	Cancer/testis antigen 11.4; Cancer/testis antigen family 11 member 4; CT11.4; dJ171K16.1; Nuclear associated protein SPAN Xd; Nuclear-associated protein SPAN-Xd; SPAN Xd protein; SPANX C; SPANX D; SPANX family member D; SPANX-D; SPANXD; Sperm protein associated with the nucleus on the X chromosome D; Sperm protein associated with the nucleus X chromosome family member D; SPNXD_HUMAN.
Research Area	Tumour  Cell biology  Developmental biology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	11kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SPANXD/CT11.4: 21-80/97
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a sperm protein that is associated with the nucleus but, although a role in spermatogenesis is suggested, the specific function of this family member has not yet been determined. Polymorphisms in this gene may be associated with prostate cancer susceptibility. [provided by RefSeq, Apr 2014] Subcellular Location: Cytoplasm. Nucleus. Associated with nuclear craters. Tissue Specificity: Detected in testis, sperm and a melanoma cell line. Similarity: Belongs to the SPAN-X family. SWISS: Q9BXN6 Gene ID: 64648 Database links: Entrez Gene: 64648 Human Omim: 300670 Human SwissProt: Q9BXN6 Human Unigene: 375036 Human

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