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Product Name Oxytocin Chinese Name 催产素抗体 Alias MGC126890; MGC126892; NEU1_HUMAN; Neurophysin 1; Neurophysin 1 Precursor; Neurophysin I; Ocytocin; OT; OT NPI; OXT; Oxy; Oxytocin neurophysin 1 precursor; Oxytocin Neurophysin preproprotein; Oxytocin prepro (neurophysin I); Oxytocin prepropeptide; Oxytocin-neurophysin 1. literatures Specific References (2) | SL17581R has been referenced in 2 publications.[IF=2.445] Yuan Z et al. Seasonal expressions of oxytocin and oxytocin receptor in the epididymides in the wild ground squirrels (Citellus Dauricus Brandt). Gen Comp Endocrinol. 2020 Apr 1;289:113391. WB&IHC-P ; Wild ground squirrel.[IF=2.136] Liu Q et al. Seasonal expressions of oxytocin and oxytocin receptor in epididymis of the male muskrat (Ondatra zibethicus).(2018) Theriogenology.124:24-31. IHC ; muskrat.Research Area Cell biology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, Guinea Pig, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 1.0kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Oxytocin: 20-28/125 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013]
Function:
Neurophysin 1 specifically binds oxytocin.
Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland.
Subcellular Location:
Secreted
Similarity:
Belongs to the vasopressin/oxytocin family.
SWISS:
P01178
Gene ID:
5020
Database links:Entrez Gene: 5020 Human
Entrez Gene: 18429 Mouse
Omim: 167050 Human
SwissProt: P01178 Human
SwissProt: P35454 Mouse
SwissProt: P13389 Sheep
Unigene: 113216 Human
Unigene: 48915 Rat
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