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Product Name OXSM Chinese Name β-酮脂酰合成酶/β-ketoacyl synthase抗体 Alias 3 oxoacyl ACP synthase, mitochondrial; 3 oxoacyl acyl carrier protein synthase; 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; Acyl malonyl acyl carrier protein condensing enzyme; Beta ketoacyl ACP synthase; beta-ketoacyl synthase; beta-ketoacyl synthase, mitochondrial; Beta-ketoacyl-ACP synthase; C80494; FASN2D; FLJ20604; KASI; KS; OXSM; OXSM_HUMAN; type II mitochondrial beta ketoacyl synthase. Research Area Tumour Cell biology Signal transduction The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 49kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human OXSM: 261-360/459 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a beta-ketoacyl synthetase. The encoded enzyme is required for elongation of fatty acid chains in the mitochondria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2009]
Function:
May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.
Subcellular Location:
Mitochondrion.
Tissue Specificity:
Widely expressed. Higher expression in heart, skeletal muscle, liver and kidney which contain high levels of active mitochondria.
Similarity:
Belongs to the beta-ketoacyl-ACP synthases family.
SWISS:
Q9NWU1
Gene ID:
54995
Database links:
Entrez Gene: 54995 Human
Entrez Gene: 71147 Mouse
Omim: 610324 Human
SwissProt: Q9NWU1 Human
SwissProt: Q9D404 Mouse
Unigene: 55781 Human
Unigene: 197960 Mouse
Unigene: 24121 Rat
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