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Rabbit Anti-OXCT2 antibody
Rabbit Anti-OXCT2 antibody
3 oxoacid CoA transferase 2; 3-oxoacid CoA-transferase 2A; FKSG25; mitochondrial; OXCT2; SCOT T; SCOT-t; SCOT2_HUMAN; SCOTT; Succinyl CoA:3 ketoacid coenzyme A transferase 2, mitochondrial; Succinyl-CoA:3-ketoacid coenzyme A transferase 2; Testis specific
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  • NO.:SL17575R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name OXCT2
Chinese Name OXCT2蛋白抗体
Alias 3 oxoacid CoA transferase 2; 3-oxoacid CoA-transferase 2A; FKSG25; mitochondrial; OXCT2; SCOT T; SCOT-t; SCOT2_HUMAN; SCOTT; Succinyl CoA:3 ketoacid coenzyme A transferase 2, mitochondrial; Succinyl-CoA:3-ketoacid coenzyme A transferase 2; Testis specific succinyl CoA:3 oxoacid CoA transferase; Testis-specific succinyl-CoA:3-oxoacid CoA-transferase.  
Research Area Cell biology  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 52kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human OXCT2: 401-500/517 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail OXCT2 is a testis-specific succinyl-CoA:3-oxoacid CoA transferase (EC 2.8.3.5), which catalyzes the reversible transfer of CoA from succinyl-CoA to acetoacetate in the first step of ketone body utilization. See also OXCT1 (MIM 601424).[supplied by OMIM, Mar 2008]

Function:
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

Subcellular Location:
Mitochondrion.

Tissue Specificity:
Testis specific.

Similarity:
Belongs to the 3-oxoacid CoA-transferase family.

SWISS:
Q9BYC2

Gene ID:
64064

Database links:

Entrez Gene: 64064 Human

Omim: 610289 Human

SwissProt: Q9BYC2 Human

Unigene: 472491 Human



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