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Product Name OVGP1 Chinese Name 输卵管特异性glycoprotein抗体 Alias CHIT5; EGP; Estrogen dependent oviduct protein; Estrogen-dependent oviduct protein; MUC9; mucin 9; Mucin-9; OGP; OVGP 9; Ovgp1; OVGP1_HUMAN; Oviduct glycoprotein; Oviduct-specific glycoprotein; Oviductal glycoprotein; Oviductin. Research Area Cell biology Developmental biology Cell adhesion molecule glycoprotein Cell type markers Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 73kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human OVGP1: 51-150/678 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a large, carbohydrate-rich, epithelial glycoprotein with numerous O-glycosylation sites located within threonine, serine, and proline-rich tandem repeats. The gene is similar to members of the mucin and the glycosyl hydrolase 18 gene families. Regulation of expression may be estrogen-dependent. Gene expression and protein secretion occur during late follicular development through early cleavage-stage embryonic development. The protein is secreted from non-ciliated oviductal epithelial cells and associates with ovulated oocytes, blastomeres, and spermatozoan acrosomal regions. [provided by RefSeq, Jul 2008]
Function:
Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development.
Subcellular Location:
Cytoplasmic vesicle; secretory vesicle. Secretory granules.
Tissue Specificity:
Oviduct.
Similarity:
Belongs to the glycosyl hydrolase 18 family.
SWISS:
Q12889
Gene ID:
5016
Database links:Entrez Gene: 5016 Human
Entrez Gene: 12659 Mouse
Omim: 603578 Human
SwissProt: Q12889 Human
SwissProt: Q62010 Mouse
Unigene: 1154 Human
Unigene: 431947 Mouse
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