Product Name	OTUD6B
Chinese Name	OTUD6B蛋白抗体
Alias	CGI-77; DUBA-5; DUBA5; OTU domain containing protein 6B; OTU domain-containing protein 6B; OTU6B_HUMAN; OTUD6B.
literatures	Specific References  (1)     |     SL17567R has been referenced in 1 publications. [IF=3.249] Zhongqun Wang. et al. Loss of OTUD6B Stimulates Angiogenesis and Promotes Diabetic Atherosclerosis. DIABET METAB SYND OB. 2022 Sep;15:3027-3038  IF, WB ;  Mouse.   PubMed:36200061
Research Area	Tumour  Cell biology  Cyclin  b-lymphocyte  Epigenetics  Ubiquitin
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Dog, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	34kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human OTUD6B: 51-150/293
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the ovarian tumor domain (OTU)-containing subfamily of deubiquitinating enzymes. Deubiquitinating enzymes are primarily involved in removing ubiquitin from proteins targeted for degradation. This protein may function as a negative regulator of the cell cycle in B cells. [provided by RefSeq, Nov 2013] Similarity: Contains 1 OTU domain. SWISS: Q8N6M0 Gene ID: 51633 Database links: Entrez Gene: 51633 Human Entrez Gene: 72201 Mouse Omim: 612021 Human SwissProt: Q8N6M0 Human SwissProt: Q8K2H2 Mouse Unigene: 30532 Human Unigene: 387724 Mouse
Product Picture	Sample: Jurkat(Mouse) Cell Lysate at 40 ug Primary: Anti-OTUD6B (SL17567R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34 kD Observed band size: 34 kD Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (OTUD6B) Polyclonal Antibody, Unconjugated (SL17567R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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